ProteomicsCenter.nl 

2006

» Gideon Lansbergen, Ilya Grigoriev, Yuko Mimori-Kiyosue, Toshihisa Ohtsuka, Susumu Higa, Isao Kitajima, Jeroen Demmers# , Niels Galjart, Adriaan B. Houtsmuller, Frank Grosveld and Anna Akhmanova (2006) CLASPs attach microtubule plus ends to the cell cortex through a complex with LL5β. Dev Cell 11: 21-32.

» Gert-Jan C. M. van den Bemd, Jeroen Krijgsveld, Theo M. Luider, Angelique L. van Rijswijk, Jeroen A. A. Demmers# , and Guido Jenster (2006) Mass spectrometric identification of human prostate cancer-derived proteins in serum of xenograft-bearing mice. Mol Cell Proteomics 5: 1830-9.

» Mari, P.O., Florea, B.I., Persengiev, S.P., Verkaik, N.S., Brüggenwirth, H.T., Modesti, M., Giglia-Mari, G., Bezstarosti, K.#, Demmers, J.A.A.# , Luider, T.M., Houtsmuller, A.B., & Van Gent, D.C. (2006) Dynamic Assembly of End-joining Complexes Requires Interaction between Ku70/80 and XRCC4. Proc Natl Acad Sci USA 103: 18597-602.

2007

» Carmen Sánchez, Inés Sánchez, Jeroen A. A. Demmers# , Patrick Rodriguez, John Strouboulis & Miguel Vidal (2007) Proteomic analysis of RING1B / RNF2 interactors identifies a novel complex with the FBXL10 / JMJD1B histone demethylase and the BCOR corepressor. Mol Cell Proteomics 6: 820-34.

» Ilya Grigoriev, Daniël Splinter, Nanda Keijzer, Phebe S. Wulf, Jeroen Demmers# , Toshihisa Ohtsuka, Mauro Modesti, Ivan V. Maly, Frank Grosveld, Casper C. Hoogenraad and Anna Akhmanova (2007) Rab6 regulates transport and targeting of exocytotic carriers. Dev Cell 13: 305-14.

» Eva Teuling, Suaad Ahmed, Elize Haasdijk, Jeroen Demmers#, Michel O Steinmetz, Anna Akhmanova, Dick Jaarsma and Casper Hoogenraad (2007) Motor neuron disease-associated mutant VAPB recruits wild type VAPs into tubular aggregates and perturbs FFAT binding. J Neurosci 27: 9801-01.

» Mauro Modesti, Magda Budzowska, Céline Baldeyron, Jeroen Demmers#, Rodolfo Ghirlando and Roland Kanaar (2007) RAD51AP1 is a structure-specific DNA binding protein that stimulates joint molecule formation during RAD51-mediated homologous recombination. Mol Cell 28: 468-481.

2008

» B. R. Prashanth Kumar, Jan A. van der Knaap, Jeroen A. A. Demmers#, Karel Bezstarosti#, Helen van Beusekom, Andrew A. Travers and C. Peter Verrijzer (2008) Ubiquitin Protease 64 Controls Cell Fate Through Stabilization of the Transcriptional Repressor Tramtrack. Mol Cell Biol 28: 1606-15.

» Dekkers DH#, Bezstarosti K#, Gurusamy N, Luijk K, Verhoeven AJ, Rijkers EJ#, Demmers JA#, Lamers JM, Maulik N, Das DK (2008) Identification by a differential proteomic approach of the induced stress and redox proteins by resveratrol in the normal and diabetic rat hearts. J Cell Mol Med, 12(5A):1677-89.

» Ilya Grigoriev, Susana Montenegro Gouveia, Babet van der Vaart, Jeroen Demmers#, Jeremy T. Smyth, Srinivas Honnappa, Daniël Splinter, Michel O. Steinmetz, James W. Putney, Jr, Casper C. Hoogenraad and Anna Akhmanova (2008) STIM1 is a microtubule plus end tracking protein involved in remodeling of the endoplasmic reticulum. Curr Biol 18: 177-82.

» Gillian E. Chalkley, Yuri M. Moshkin, Karin Langenberg, Karel Bezstarosti#, Andras Blastyak, Henrik Gyurkovics, Jeroen A. A. Demmers#, and C. Peter Verrijzer (2008) The Transcriptional Co-activator SAYP is a Trithorax Group Signature Subunit of the PBAP Chromatin Remodeling Complex. Mol Cell Biol 28: 2920-9.

» Debbie L. C. van den Berg, Wensheng Zhang, Adam Yates, Erik Engelen, Katalin Takacs, Karel Bezstarosti#, Jeroen Demmers#, Ian Chambers, Raymond A. Poot (2008) The Estrogen Related Receptor Beta interacts with Oct4 to positively regulate Nanog gene expression. Mol Cell Biol 28: 5986-95.

» Anna Lagarou, Adone Mohd-Sarip, Yuri M. Moshkin, Gillian E. Chalkley, Karel Bezstarosti#, Jeroen A. A. Demmers#, and C. Peter Verrijzer (2008) dKDM2 couples histone H2A ubiquitylation to histone H3 demethylation during Polycomb group silencing. Genes Dev 22: 2799-810.

2009

» J. Jaworski, L.C. Kapitein, S.M. Gouveia, B.R. Dortland, P.S. Wulf, I. Grigoriev, P. Camera, S.A. Spangler, P. Di Stefano, J. Demmers#, H. Krugers, P. Defilippi, A. Akhmanova, and C.C. Hoogenraad (2009) Dynamic Microtubules Regulate Dendritic Spine Morphology and Synaptic Plasticity. Neuron 61: 85-100.

» Gontan C, Güttler T, Engelen E, Demmers J#, Fornerod M, Grosveld FG, Tibboel D, Görlich D, Poot RA, Rottier RJ. (2009) Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors. J Cell Biol 185: 27-34.

» Niessen, HEC, Demmers, JAA# & Voncken, JW (2009) Talking to chromatin: post-translational modulation of polycomb group function. Epigenetics & Chromatin 2:10.

» Yuri M Moshkin, Tsung Wai Kan, Henry Goodfellow, Karel Bezstarosti#, Robert K Maeda, Maxim Pilyugin, Francois Karch, Sarah Bray, Jeroen A. A Demmers# & Peter Verrijzer (2009) Histone Chaperone ASF1 Cooperates with a LID/KDM5 Histone H3K4me2/3 Demethylase Complex to Mediate Gene-Selective Silencing. Mol Cell, 35(6):782-93.

» Maxim Pilyugin, Jeroen Demmers#, Peter C. Verrijzer, Francois Karch, and Yuri M. Moshkin (2009) Phosphorylation-mediated control of histone chaperone ASF1 levels by Tousled-like kinases. PLoS ONE 4(12):e8328.

» Wong HY, Demmers JA#, Bezstarosti K#, Grootegoed JA, Brinkmann AO (2009) DNA dependent recruitment of DDX17 and other interacting proteins by the human androgen receptor. Biochim Biophys Acta 1794(2):193-8.

2010

» Karel Bezstarosti*#, Alireza Ghamari*, Frank G. Grosveld, Jeroen A. A. Demmers#. Differential proteomics based on 18O labeling to determine the Cyclin Dependent Kinase 9 interactome. J Proteome Res 9(9):4464-75.

» Reddy BA, Bajpe PK, Bassett A, Moshkin YM, Kozhevnikova E, Bezstarosti K#, Demmers JA#, Travers AA, Verrijzer CP. Drosophila Transcription Factor Tramtrack69 Binds MEP1 to Recruit the Chromatin Remodeler NuRD. Mol Cell Biol 30(21):5234-44.

» David Landeira, Stephan Sauer, Raymond Poot, Maria Dvorkina, Luca Mazzarella, Helle F. Jørgensen, C. Filipe Pereira, Marion Leleu, Francesco M. Piccolo, Mikhail Spivakov, Emily Brookes, Ana Pombo, Cynthia Fisher, William C. Skarnes, Tim Snoek, Karel Bezstarosti#, Jeroen Demmers#, Robert J. Klose, Miguel Casanova, Ligia Tavares, Neil Brockdorff, Matthias Merkenschlager & Amanda G. Fisher. Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators. Nat Cell Biol, 12(6):618-24.

» Arnaud Krebs, Jeroen Demmers#, Krishanpal Karmodiya, Nan-Chi Chang, Alice Chien Chang, László Tora. ATAC and Mediator coactivators form a stable complex to regulate a set of non-coding RNA genes. EMBO Rep 11(7):541-7.

» van den Berg DL, Snoek T, Mullin NP, Yates A, Bezstarosti K#, Demmers J#, Chambers I, Poot RA. An Oct4-centered protein interaction network in embryonic stem cells. Cell Stem Cell 6(4):369-81.

» Daniël Splinter, Marvin E. Tanenbaum, Arne Lindqvist, Dick Jaarsma, Annette Flotho, Ka Lou Yu, Ilya Grigoriev, Dieuwke Engelsma, Elize D. Haasdijk, Nanda Keijzer, Jeroen Demmers#, Maarten Fornerod, Frauke Melchior, Casper C. Hoogenraad, René H. Medema & Anna Akhmanova. Bicaudal D2, Dynein, and Kinesin-1 Associate with Nuclear Pore Complexes and Regulte Centrosome and Nuclear Positioning during Mitotic Entry. PLoS Biology 8(4): e1000350. doi:10.1371/journal.pbio.1000350.

» van Dijk TB, Gillemans N, Stein C, Fanis P, Demmers J#, van de Corput M, Essers J, Grosveld F, Bauer UM, Philipsen S. Friend of Prmt1, a novel chromatin target of protein arginine methyltransferases. Mol Cell Biol 30(1):260-72.

Van de Nobelen S, Rosa-Garrido M, Leers J, Heath H, Soochit W, Joosen L, Jonkers I, Demmers J#, van der Reijden M, Torrano V, Grosveld F, Delgado MD, Renkawitz R, Galjart N, Sleutels F. CTCF regulates the local epigenetic state of ribosomal DNA repeats. Epigenetics Chromatin 3(1):19.

Kubben N, Voncken JW, Demmers J#, Calis C, van Almen G, Pinto Y, Misteli T. Identification of differential protein interactors of lamin A and progerin. Nucleus 1(6):513-525.  

2011

» Soler E, Andrieu-Soler C, Boer E, Bryne JC, Thongjuea S, Rijkers E#, Demmers J#, Ijcken W, Grosveld F (2011) A systems approach to analyze transcription factors in mammalian cells. Methods 53(2):151-62.

Casanova M, Preissner T, Cerase A, Poot R, Yamada D, Li X, Appanah R, Bezstarosti K#, Demmers J#, Koseki H, Brockdorff N. Polycomblike 2 facilitates the recruitment of PRC2 Polycomb group complexes to the inactive X chromosome and to target loci in embryonic stem cells. Development [Epub ahead of print]

Engelen E, Akinci U, Bryne JC, Hou J, Gontan C, Moen M, Szumska D, Kockx C, van Ijcken W, Dekkers DH#, Demmers J#, Rijkers EJ#, Bhattacharya S, Philipsen S, Pevny LH, Grosveld FG, Rottier RJ, Lenhard B, Poot RA (2011) Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes. Nat Genet 43(6):607-11.

Grigoriev I, Yu KL, Martinez-Sanchez E, Serra-Marques A, Smal I, Meijering E, Demmers J#, Peränen J, Pasterkamp RJ, van der Sluijs P, Hoogenraad CC, Akhmanova A (2011) Rab6, Rab8, and MICAL3 Cooperate in Controlling Docking and Fusion of Exocytotic Carriers. Curr Biol 21(11):967-74.

Esteghamat F, van Dijk TB, Braun H, Dekker S, van der Linden R, Hou J, Fanis P, Demmers J#, van Ijcken W, Ozgur Z, Horos R, Pourfarzad F, von Lindern M, Philipsen S (2011) The DNA binding factor Hmg20b is a repressor of erythroid differentiation. Haematologica [Epub ahead of print]

Meenhuis A, van Veelen PA, de Looper H, van Boxtel N, van den Berge IJ, Sun SM, Taskesen E, Stern P, de Ru AH, van Adrichem AJ, Demmers J#, Jongen-Lavrencic M, Löwenberg B, Touw IP, Sharp PA, Erkeland SJ (2011) MiR-17/20/93/106 promote hematopoietic cell expansion by targeting sequestosome 1-regulated pathways in mice. Blood [Epub ahead of print]

Kapitein LC, Yau KW, Gouveia SM, van der Zwan WA, Wulf PS, Keijzer N, Demmers J#, Jaworski J, Akhmanova A, Hoogenraad CC (2011) NMDA Receptor Activation Suppresses Microtubule Growth and Spine Entry. J Neurosci 31(22):8194-209.

Van der Vaart B, Manatschal C, Grigoriev I, Olieric V, Gouveia SM, Bjelic S, Demmers J#, Vorobjev I, Hoogenraad CC, Steinmetz MO, Akhmanova A (2011) SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase. J Cell Biol 193(6):1083-99.

Cui S, Kolodziej K, Obara N, Amaral-Psarris A, Demmers J#, Shi L, Engel JD, Grosveld F, Strouboulis J, Tanabe O (2011) Nuclear Receptors TR2 and TR4 Recruit Multiple Epigenetic Transcriptional Co-repressors that Associate Specifically with the Embryonic {beta}-type Globin Promoters in Differentiated Adult Erythroid Cells. Mol Cell Biol [Epub ahead of print]