Welcome!
The Proteomics Center
at Erasmus MC develops mass spectrometry based proteomics methodologies for the qualitative and quantitative analysis of (sub)proteomes
and provide proteomics services
for the Erasmus MC scientific community and for external
researchers. The research projects in our laboratory focus on the
elucidation of protein complex composition, the analysis of protein posttranslational modifications ('functional proteomics')
and on the analysis of (sub)cellular proteomes and the dynamics
thereof. For this, we use high sensitivity and high accuracy, quantitative mass spectrometry (nanoLC-MS/MS)
combined with SILAC, dimethylation, 18O and isobaric (iTRAQ/TMT) labeling.
In addition, we are developing
software tools for better presentation and comprehensive interpretation of proteomics experiments. The ultimate goal of our research is to
develop analytical tools to better understand how cellular processes are controlled at the molecular level.
| The Proteomics Center is supported by: | |
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